What Exactly is Forskolin?
The Latin name for Forskolin (also called coleonol) is coleus forskohlii, and it is a labdane diterpene whose source is a plant called Indian Coleus. In fact, it is usually used as a biochemical tool for the purpose of increasing the levels of cAMP (or cyclic AMP, a vital second messenger needed for a proper biological feedback by cells to hormones as well as other extracellular indicators) within the study of the physiology of cells. Thus, this supplement activates what is called adenylate cyclase, which is a specific enzyme that exists in mammals and a catalyst for transforming of one enzyme into another (to be precise: ATP into cAMP). The ultimate result of this is that these enzymes naturally stimulate the metabolism of the body, its use of energy and ultimately, the ability of the body to burn fat. As a consequence, this natural chemical compound is becoming increasingly more popular due to its being associated with the potential for being a catalyst for weight loss, as well as an accelerator for building muscle.
In short, this is what this means:
The enzyme called adenylate cyclase which is obtained from cAMP has the function of setting off a variety of organisms into action. cAMP is a type of enzyme which is identified as a “second messenger” which means that it helps to boost neurotransmitter activity. So, due to this amazingly useful enzyme as well as the valuable effects it is claimed to have, it is considered that pure and natural supplements of forskolin extract are linked with a possible improvement of cardiovascular functions, an increase of memory, as well as supporting the activation of quicker and more efficient mechanisms for the loss of body fat.
Hold on. How does it work?
This is how Forskolin works: it is a well known fact that the human body utilizes enzymes for the conversion of energy that is not used (in short: glucose) into deposits of fat in the body. Thus, Forskolin revs up the enzyme adenylate cyclase, which in turn aids in helping the cells of cAMP to melt the stored fat. As an added bonus, this natural supplement also serves as an appetite suppressant while also increasing lean body bulk. And, as a consequence of all the above, the body will incite a breakdown of the fat cells which have been stored, which results in an increase of the metabolism as well as fat cells being burnt off. Hence, weight loss!
Why is there such an interest in this chemical complex at this moment in time?
It can be said that this herbal medicine is as old as man and that it has been used for a long time. In fact, Forskolin in its pure and natural form is an extraordinary herbal extract as well as a multi-use fragrant herbal component (in fact, it is called bioactive labdane diterpene, and exists in no other supplement but this one!). As it has been mentioned, it is a derivative from the plant Plectranthus Barbatus/Lamiaceae, or rather, from its roots. This medicinal herb has been and continues to be a vital plant all over the world, particularly in the time-honored Indian Ayurvedic remedy. The reason for this is that it possesses very valuable anti-inflammatory as well as anti-microbial properties (and a variety of pharmacological advantages).
The deeply-rooted origin of this magical plant stems from the mint plant family. It can normally be found in locations within the eastern hemisphere, such as India, Thailand, Burma, as well as some sections of Africa and Brazil. As a matter of fact, the story of this Indian-originating coleus perennial herb genus (named coloneol as well as makandi) is quite a long one, as it has been connected to very old herbal tonic medication which was used for treating a wide array of conditions and disorders, such as the following:
• disorders of the central nervous system
• cardiovascular and circulation conditions
• infections, skin problems, eczema and boils
• disorders of the digestive and gastrointestinal system
• coughs and respiratory disorders
• rheumatism and stiffness of the body
And in addition to all this, it has recently been acclaimed as one of the most effective herbal supplements for its effects in fat burning. But there will be more on this…
But how is it possible that an ordinary herbal extract can be so powerful?
To put it quite simply, what Forskolin is, is this: a cyclic AMP agonist (which is defined as being chemical which attaches itself to receptors in order to activate them and create a biological feedback). Thereby, this herbal extract is well-known for the following: it naturally activates, controls and regulates adenylate cyclase (this is an enzyme which is related to various useful glycogen as well as lipid metabolism functions and it is also a vital enzyme which incites the producing of what is called cAMP (short for cyclic adenosine monophosphate). In turn, this enzyme is very closely linked with ATP (an abbreviation for adenosine triphosphate) which has incredible properties, such as the following:
• it can help decrease inflammation
• it can provide help with hypothyroidism
• aiding bronchodilation/lung health
• helps with glaucoma conditions
• it can help with problems with any allergies
• aids in the prevention of platelet aggregation
• aids in clearing acne from the skin
• it is important for reducing blood pressure
• also helps with possible depression
• helps with blood circulation
• and, it provides positive inotropic actions within the heart
Now, this may be the reason why it’s so popular in this day and age.
One of the main reasons why this herbal magic is becoming more and more popular is that its largest and most sought-after advantages originate from the activating of cellular adenylate cyclase. In turn, this enzyme has an intrinsic capability of stimulating hormones that set off the needed mechanisms which in turn burn the fat in the body. The result of this has caused a large weight loss debate regarding this plant. In fact, it all started with famed The Dr Oz Show.
What is this show about?
The Dr Oz Show is a TV talk show hosted by the Turkish-American Columbia University professor and heart surgeon Dr Mehmet Oz, who gained fame by presenting this show, started by the famous Oprah Winfrey and her Harpo company. This show has set off many controversies, as the medical community has claimed that more than 50 percent of the medical recommendations had no serious scientific base. However, Forskolin became quite famous when Dr Oz called it a ‘miracle flower’ and it had a screening for more than 5 minutes, whereupon the famous medical show host also dubbed is a ‘rapid belly melt’. As a consequence, it became incredibly popular among those interested in weight loss.
This particular herbal supplement is considered a catalyst for weight loss: is this mere publicity or is there some truth in it?
It is without any doubt at all that the weight loss industry makes a profit of over 60 million dollars a year throughout the world (remaining one of the most money-making industries ever, as it seems many people have the desire to attempt to remain sexy and young). Also, the increasing trend in seeking a magical formula for looking slim but remaining healthy are natural alternatives, rather than those which can imperil the health. But also, many of those who are morbidly obese or seriously overweight are aware that their condition could lead to great health problems as well as complications if the conditions are not taken care of in time and in a proper and healthy manner.
There are some studies which claim that supplements of Forskolin can alter the composition of the body into lean muscle mass in as a mere twelve weeks, on the condition that they are used every day. It seems, in fact, that body fat simply vanishes, being replaced by healthy weight and muscles. It is relevant to note that those subjected to the testing were fighting against obesity, but there was no need for them to exercise in achieving the mentioned effects.
So, let’s be honest: can this plant extract really assist in burning body fat? After all, there seems to be a lot of hype about it all.
It cannot be repeated enough and it never stops being valid that nothing, absolutely nothing, can be more beneficial than simple exercising, a proper and healthy diet and good nutrition habits, as well as other important lifestyle options (whole foods being one of the biggest benefits for the body, as well as a sensible and healthy choice of foods and drinks).
The fuss and controversy concerning the Forskolin extract is mostly owing to the immediate connection which it has with the burning off of body fat more rapidly compared with the usual dietary supplements. This is due to it being discovered that the plant extract can aid in breaking down belly fat (which is really merely adipose tissue), which in turn assists in releasing fatty acids within a process which is known under the name of thermogenesis (and which involves the process of hydrating in the aim of flushing, eliminating as well as removing body debris and toxic waste matter). In the course of the procedure of revving up thermogenesis, a swifter metabolic rate is naturally incurred which in turn raises the inner body temperature, and as a result, added surplus calories as well as body weight is burned off and melted.
Thus, as far as the average adult person is concerned, this is an excellent fat burner which can assist in burning body fat as well as losing some kilograms. In fact, it can be said that it is the best way of jumpstarting the process of losing weight. The truth is that there is no magical formula for losing weight but it is without doubt that this plant may be a superb way of developing a starting point in having a healthier and slimmer body. What many medical professionals recommend is to find a Forskolin plant supplement which has the option of a free trial and which can offer you the opportunity to try out the plant extract and see what kind of effect it has on the body.
What, if any, are the possible side effects of Forskolin, the herbal supplement?
All supplements inevitably have possible side effects, and so it is with Forskolin. They are the following:
– possible throat irritation – this can occur mostly during the inhaling of Forskolin;
– anorectal itching – some studies on laboratory mice have shown that significant doses of this plant extract can cause anorectal itching, although the studies are not conclusive;
– tingling of the skin – this can occur only when the extract is taken in the form of eye drops;
– flushing or low blood pressure – this happens as a rule with intravenous administrating of the plant extract in treating infections, although this does not occur in OTC forms of the herbal supplement;
– a suppression of the central nervous system – substantial dosages can be the cause of depression in lab mice, even if these kinds of doses can be avoided when give different supplement forms but this side effect has not thus far been seen in human beings.
Also, it is advisable that the Forskolin herbal extract is not taken in the case of the following health problems or disorders:
– Those with heart problems should abstain from partaking in this herb, as it can impede the effect of some medicaments and cause a reduction of the blood pressure.
– This herbal extract should not be taken in the case of the existing of any blood disorders.
– The disease of polycystic kidney – some molecules which are restricted to this plant were discovered in kidney cysts, which means that those suffering from this disease should avoid Forskolin.
– Thus far, no definitive studies have been carried out on the effects of this plant extract on pregnant women, and so it is best for women in this state to stay away from it.
In addition, those taking the following medicaments should keep away from this extract:
• Certain medications for diabetes – there have been no solid studies conducted so far, although some possible interactions can be expected;
• Vasodilators can exacerbate medicaments which can cause the dilating of blood vessels (for hypercholesterolemia/hypertension);
• CYP3A-dependent medication, most regularly used for liver diseases and disorders;
• Anticoagulant or blood-thinning medication, whose effects can be enhanced by Forskolin;
• Antihypertensives (drugs which aid in lowering blood pressure) and their effects can also be enhanced by using this plant extract.
So, in conclusion, who can use Forskolin?
We talked about pregnant women, but how about mothers who are nursing? Is it safe for them to use Forskolin? Well, just like a great number of supplements, this one also is not on the recommended list. In the case that a physician approves its usage, the expecting or nursing mother needs to be careful in monitoring her own health and the health of her baby to ensure that there are no complications. Although in truth, it is best to steer well away from all kinds of supplements in the case of expecting or nursing mothers.
When it comes to children, there should be extreme caution practiced, as supplements are not designed for the use of young children. In spite of the fact that there is no proof that this supplement has negative effects on kids, still, it is a strong recommendation that kids younger than 18 avoid most dietary supplements, including this one. This in no way means that this herbal extract can cause serious problems with the health, but to be more precise, it is not known if Forskolin can cause harmful effects.
What dosages should be used?
In the case that you are still unsure about the effects of Forskolin but would like to try it out for its alleged benefits, what is recommended is not more than the amount of 25 – 60 milligrams a day, which gives the body the chance to adjust as well as adapt to it. The market offers Forskolin tablets (125 milligrams) and Forskolin capsules (250 milligrams, twice a day is recommended, meaning two capsules daily) – and this entails a totally natural and unadulterated extract. It is also important to say that, upon opting for a supplement, you need to ensure that you get one with no extra fillers of additives, as well as making sure that it contains 20 percent of unadulterated Forskolin extract at the very least (or even higher). We stress once more that it is vital that the right kind of extract is used as the worst thing you could do is get a supplement that is not pure and all natural! Even though this extract is believed to be an amazing fat burner, we need time to figure out if it is right for us.
Some reviews for Forskolin:
We already mentioned Dr Oz, a physician and TV show host who is an avid promoter of this herbal extract, and has done a lot to endorse the product and give it worthy credibility. He is the host of a very popular and well watched TV show and in fact, he has several times invited guests as well as experts to his show, those who have taken the supplement successfully.
Another review is the site Drugs.com, which is a dependable online source writing about authentic information regarding supplements and other medicaments. Its review of Forskolin is quite positive.
There is, however, also a negative review by the NYU Langone Medical Center. This center mentions the supplement, stating that there is no scientific evidence which can sustain the claimed benefits of using it.